Human Papillomavirus and Cervical Cancer Infection Discuss the below Mini Case Study:A 36-year-old female has a routine physical. She is single, doesn’t smoke and hasa few drinks of alcohol a week. Sh
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Human Papillomavirus and Cervical Cancer Infection
Discuss the below Mini Case Study:A 36-year-old female has a routine physical. She is single, doesn’t smoke and hasa few drinks of alcohol a week. She began menarche at age 11 and her first sexualintercourse was at age 14. She has had numerous sexual partners and does notregularly use barrier contraception. Physical examination is normal. The Papsmear comes back as atypical squamous cells of undetermined significance(ASCUS).a. What risk factors does she have for cervical cancer?b. Describe the pathogenesis of Human Papilloma Virus.c. Why should HPV testing be done and what are the tests to be ordered?d. What HPV subtypes are associated with cervical cancer?e. Explain the role of E6 and E7 HPV proteins in cervical cancer.f. Differentiate between Human Papilloma Virus and Herpes Simplex virus*** Be sure to substantiate your comments by stating the reasons and relatinganswers to evidence-based material. Include textbook and journal citations.Demonstrate organization, originality, and clarity of thought. Integrate yourreadings with examples from your personal experience and practice wherepossible
Human Papillomavirus and Cervical Cancer Infection Discuss the below Mini Case Study:A 36-year-old female has a routine physical. She is single, doesn’t smoke and hasa few drinks of alcohol a week. Sh
Discuss the below Mini Case Study: A 36-year-old female has a routine physical. She is single, doesn’t smoke and has a few drinks of alcohol a week. She began menarche at age 11 and her first sexual intercourse was at age 14. She has had numerous sexual partners and does not regularly use barrier contraception. Physical examination is normal. The Pap smear comes back as atypical squamous cells of undetermined significance (ASCUS). a. What risk factors does she have for cervical cancer? b. Describe the pathogenesis of Human Papilloma Virus. c. Why should HPV testing be done and what are the tests to be ordered? d. What HPV subtypes are associated with cervical cancer? e. Explain the role of E6 and E7 HPV proteins in cervical cancer. f. Differentiate between Human Papilloma Virus and Herpes Simplex virus *** Be sure to substantiate your comments by stating the reasons and relating answers to evidence-based material. Include textbook and journal citations. Demonstrate organization, originality, and clarity of thought. Integrate your readings with examples from your personal experience and practice where possible
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